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In the 16th century, satirists made physicians a favorite target, resembling Molière's caricature whose prescription for anything was "clyster, bleed, purge," or "purge, bleed, clyster." In Roper's biography of his father-in-law Sir Thomas More, he tells of Thomas More's eldest daughter falling sick of the sweating sickness. After praying, it came to Thomas More: There straightway it came into his mind that a clyster would be the one way to help her, which when he told the physicians, they at once confessed that if there were any hope of health, it was the very best help indeed, much marveling among themselves that they had not afore remembered it.
In the 18th century tobacco smoke enemas were used to resuscitate drowned people.
The Maya in their late classic age (7th through 10th centuries CE) used enemas for, at least, ritual purposes, in the Xibalban court of the God D whose worship included ritual cult paraphernalia.
It is hypothesized that these enemas were for ritual purification and the ingestion of intoxicants and hallucinogens.
There are arguments both for and against colonic irrigation in people with diverticulitis, ulcerative colitis, Crohn's disease, severe or internal hemorrhoids or tumors in the rectum or colon, and its usage is not recommended soon after bowel surgery (unless directed by one's health care provider).
Regular treatments should be avoided by people with heart disease or renal failure.
Clysters were administered for symptoms of constipation and, with more questionable effectiveness, stomach aches and other illnesses.
In his early-modern treatise, The Diseases of Women with Child, François Mauriceau records that both midwives and man-midwives commonly administered clysters to labouring mothers just prior to their delivery.
Molière, in several of his plays, introduces characters of incompetent physicians and apothecaries fond of prescribing this remedy, also discussed by Argan, the hypochondriac patient of Le Malade Imaginaire.
Colonics are inappropriate for people with bowel, rectal or anal pathologies where the pathology contributes to the risk of bowel perforation.
Enema comes from Greek ἔνεμα (énema), from ἐνίημι (eníēmi), "(I) inject".
Later there came to be a device to allow gravity to infuse the solution into the recipient, consisting of a rubber bag or bucket connected to a hose with a nozzle at the other end to insert into the patient's anus, the bag or bucket being held or hung above the patient.
These continue to be used, although rubber has been replaced by modern materials and the bags, at least in hospital use, as disposable.However, he also mentions the astonishment of the King and Mme de Maintenon that she should take it before them.